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Peer review Peer review information Nature Communications thanks Rudolf Oehler, Robert Hoffman and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

The search strategy is provided in the Supplementary file

This oxidative damage severely impairs the mitochondria's ability to produce adenosine triphosphate (ATP), the currency of cellular energy

However, FINO2 indirectly inhibits GPX4 enzymatic function and directly induces ferrous (Fe 2+ ) production [39]

116,153 For example, the third-generation BCR-ABL inhibitor ponatinib forms novel hydrophobic and van der Waals interactions with the T315I-mutated ABL kinase, providing precise inhibition of resistance in acute lymphoblastic leukemia

doi: 10.1155/2017/1202459 79 WitchelSFOberfieldSEPeaAS